Alzheimers Disease


Welcome to the Alzheimers and Degenerative Disorders information page.

Cognitive Dysfunction Treatment with Non-invasive Deep Brain Stimulation

Brain Stimulation Shows Early Promise Against Alzheimer's ...

www.webmd.com/alzheimers/.../brain-stimulation-shows-early-promise-a...

TUESDAY, May 6, 2014 (HealthDay News) -- Four of six Alzheimer's patients responded to deep brain stimulation in a pilot study

 ADvance Deep Brain Stimulation in Patients with Mild ...

www.nia.nih.gov/alzheimers/.../advance-deep-brain-stimulation-patients-...

The primary purpose of this study is to evaluate the safety of deep brain stimulation of a brain structure called the fornix (DBS-f) in people with mild Alzheimer's ...

 Brain Stimulation for Combating Alzheimer's Disease at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040449/

There is solid evidence that high-frequency rTMS over the DLPFC is superior to low-frequency rTMS in treating cognitive dysfunction in AD patients as measured by the mini mental state examination (MMSE) (). The first studies using TMS in AD showed that high-frequency rTMS of the DLPFC improves naming accuracy. Transcutaneous electrical nerve stimulation (TENS) is believed to stimulate the hippocampus relevant to memory formation and the forebrain system degenerated in AD (). TENS entails current applied transcutaneously to excite nerves, enhancing cognition in AD patients (, ). The hippocampus is stimulated by TENS via spinoseptal and brainstem nuclei such as the locus coeruleus (LC) and dorsal raphe nucleus (DRN). TMS, tDCS, and DBS are the brain stimulation methods with the brightest prospects in AD patients. Increased neural activity, connectivity, and synaptic plasticity in memory and cognition-related brain areas are potential mechanisms of action.


Could Deep-Brain Stimulation Help Fight Alzheimer's?  An exciting new discovery raises hopes for treatments for memory loss. at http://www.nextavenue.org/article/2012-04/could-deep-brain-stimulation-help-fight-alzheimers